| Antidepressants Depression, Pharmacology of Depression, News |
| A wide variety of medications with different pharmacological mechanisms of action are available for treatment of depression. The antidepressants are classified into the following main groups: monoamine oxidase A inhibitors, selective serotonin reuptake inhibitors (SSRIs) , tricyclic antidepressants, and serotonin and norepinephrine reuptake inhibitors. The selective serotonin reuptake inhibitors are most widely used antidepressants because they are easy to use, and their side effects are better tolerated than those of older antidepressants. The most frequently used SSRIs are fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), and citalopram (Celexa). A newer antidepressant is venlafaxine (Effexor®), which is closely related to the SSRIs. Antidepressants are used for treatment of depression, panic disorder, obsessive-compulsive disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, social anxiety disorder etc. |
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